Primary Outcome Measures: HBsAg loss/seroconversion [ Time Frame: HBsAg level was lower than 0.05IU/mL after 96 weeks treatment ] HBsAg loss was defined as HBsAg levels 10 mIU/L was considered positive. Chronic HBV inactive carriers were enrolled in the out-patient department of Beijing Ditan Hospital. All of them were HBsAg positive and anti-HBs negative for more than 6 months with persistent undetectable HBV DNA and normal ALT levels measured at 3-6 monthly intervals during the preceding 2 years as well as with serum HBsAg levels ≤100 IU/mL determined on two occasions during the month prior to treatment. All patients did not have other liver diseases and contraindications for interferon therapy. After giving informed consent, patients were treated with weekly subcutaneous injections of peginterferon alpha-2a 180 µg. The use of other immune suppressive or regulatory drugs and other antiviral drugs was prohibited during the course of the study. In this study, the only parameter to assessing the treatment response was HBsAg level change. Treatment endpoint was HBsAg loss(＜0.05 IU/mL) and anti-HBs positive(＞10 mIU/mL) defined as seroconversion. Depending on the decli

Long-term follow-up of HBsAg clearance in patients with HBeAg-negative CHB treated with peginterferon alfa-2a (PEGASYS): increase in HBsAg clearance rate from 3% 6 months post-treatment to 8% after 3 years Reported by Jules LevinAASLD, Nov 2-6, 2007, Boston, MA P. Marcellin1, M. Brunetto2, F. Bonino3, G.K.K. Lau4, P. Farci5, C. Yurdaydin6, T. Piratvisuth7, K. Luo8, Y. Wang9, S. Hadziyais10, E. Wolf11, M. Popescu12 1Hôpital Beaujon, University of Paris, Clichy, France. 2UO Gastreonterologia ed Epatologia, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy. 3Scientific Direction, Foundation IRCCS Policlinico of Milan and University of Pisa, Italy. 4Department of Medicine, Queen Mary Hospital, Hong Kong, China. 5Dipartimento di Scienze Mediche, Università di Cagliari, Monserrato, Italy. 6Department of Gastroenterology, University of Ankara, Turkey. 7Department of Inteal Medicine, Songklanagarind Hospital, Prince of Songkla University, Hat Yai, Thailand. 8Department of Infectious Diseases, Nanfang Hospital, Guangzhou, China. 9Infectious Disease Department, Xinan Hospital, Chongqing, China. 10Department of Medicine and Hepatology, Henry Dunant Hospital, Athen

با سلام و احترام خدمت تمامی بیماران محترم ، به علت درخواست زیاد بیماران محترم و کمبود وقت جهت پاسخ گویی ، خواهشمندیم سن ، سوابق بیماری ، مصرف دارو و عکس آزمایشات قبلی + آزمایشات زیر جهت مشاوره و درمان ارسال فرمایید. شما عزیزان میتوانید ر